<div class="indexheaders">Politics and Policy&nbsp;|&nbsp;FDA Approves Pfizer's Antiretroviral Maraviroc</div> <div class="bodytext"><font size="3">[Aug 07, 2007]</font> <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <a href="http://www.fda.gov/" target="_new"><font color="#394b6b">FDA</font></a> on Monday approved <a href="http://www.pfizer.com/pfizer/main.jsp" target="_new"><font color="#394b6b">Pfizer</font></a>'s antiretroviral drug maraviroc, which belongs to a new class of antiretrovirals that could provide an alternative to HIV-positive people who have developed resistance to multiple drugs, the <a href="http://www.latimes.com/news/science/la-sci-aids7aug07,1,7014693.story?ctrack=3&amp;cset=true" target="_new"><cite><font color="#394b6b">Los Angeles Times</font></cite></a> reports (Chong, <cite>Los Angeles Times</cite>, 8/7). FDA gave expedited approval of maraviroc for use in combination with other antiretrovirals (<a href="http://www.cq.com/corp/show.do?page=products_cqhealthbeat" target="_new"><cite><font color="#394b6b">CQ HealthBeat</font></cite></a>, 8/6). <br /><br />Maraviroc works by blocking a protein, called CCR5, on human immune system cells that HIV uses as a portal to enter and infect the cell. Pfizer has proposed using the drug to treat people with advanced HIV or AIDS who have not responded to other medications. Pfizer last month also announced that maraviroc can reduce HIV viral loads among people who have never taken antiretrovirals. The company plans to offer the drug with a test developed by <a href="http://www.monogrambio.com/" target="_new"><font color="#394b6b">Monogram Biosciences</font></a> that determines if people are likely to respond to the treatment (<a href="http://www.kaisernetwork.org/daily_reports/rep_index.cfm?hint=1&amp;DR_ID=46489" target="_new"><cite><font color="#394b6b">Kaiser Daily HIV/AIDS Report</font></cite></a>, 7/26). Pfizer will sell maraviroc under the brand name Selzentry (<cite>Wall Street Journal</cite>, 8/7).<br /><br />FDA approved maraviroc on the condition that the drug's label include a black-box warning -- the "strongest possible advisory" -- according to the <cite>Times</cite>. The drug also will have a warning about an increased risk of heart attack (<cite>Los Angeles Times</cite>, 8/7). <br /><br />According to Debra Birnkrant, director of FDA's division of antiviral drug products, the approval comes after the agency concluded that HIV-positive people who have become resistant to other treatments need a new option. She added that FDA is requiring Pfizer to conduct further research into the drug's long-term side effects. According to Birnkrant, maraviroc is aimed at HIV-positive people who are quickly developing resistance to other available antiretrovirals and not people newly diagnosed as HIV-positive. For those people who are developing drug resistance to other treatments, maraviroc's "benefits clearly outweigh the risks," Birnkrant said, adding, "That doesn't mean there aren't any risks." According to a Pfizer spokesperson, maraviroc will be available in September and the wholesale cost will be about $900 monthly, the <a href="http://www.washingtonpost.com/wp-dyn/content/article/2007/08/06/AR2007080600965.html" target="_new"><cite><font color="#394b6b">AP/Washington Post</font></cite></a> reports (Neergaard, <cite>AP/Washington Post</cite>, 8/6). <br /><br />Helmut Albrecht, director the University of South Carolina's <a href="http://internalmedicine.med.sc.edu/infdis.htm" target="_new"><font color="#394b6b">Division of Infectious Diseases</font></a> who was not involved with any maraviroc trials, said he was "cautiously optimistic" about the drug. He added, "It's so completely new that it is sort of difficult to see how well this is going to do over time." The last new class of antiretrovirals was approved by FDA in 2003 (<cite>Los Angeles Times</cite>, 8/7). <br /><br />Tên thương mại của MK0518 là Maraviroc, tháng 9 sẽ có tren thị trường , và giá ban đầu là 900 Usd / tháng.... Cầu trời mau giãm giá..............<br />FDA thông báo đây là loại thuốc mạnh nhất mà chúng ta đang có để chống lại H , dòng sản phẩm này đang được nghiên cứu để phát triển mạnh hơn nữa .</p></div>

Nhung ma ko co thuoc thi dau co keo dai duoc su song phai khong ???
chung ta biet rang xa hoi nay kho chap nhan nguoi co HIV vay chung ta phai tu cuu lay chung ta thoi
Ba con nho uong thuoc deu dan va dung gio nhe
Hi ving neu duoc san xuat o viet nam MK 508 se co gia ca hop ly cho nguoi co H co the mua duoc